Biosafety/Microbiology
ABSA International-website that provides information related to biosafety
ABSA Risk Group Tool-website that allows user to look up risk groups of agents
Biosafety Cabinet Training Video-link to video for ASU's biosafety cabinet (BSC) training, recommended for anyone who uses or plans to use a BSC.
CDC Biosafety Resources and Tools - CDC Website with links to CDC resources, including laboratory biosafety guidance, risk assessments, clinical laboratory guidance, biological agent information, laboratory biosafety checklists, select agent information, packaging and shipping regulations, and laboratory acquired infections.
CDC Guidelines for Safe Work Practices in Human and Animal Medical Diagnostic Laboratories-Recommendations of a CDC-convened, Biosafety Blue Ribbon Panel
Chemical Fume Hood: How it works to protect you
Dual Use Research of Concern (DURC)-Dual use research of concern (DURC) is life sciences research that, based on current understanding, can be reasonably anticipated to provide knowledge, information, products, or technologies that could be directly misapplied to pose a significant threat with broad potential consequences to public health and safety, agricultural crops and other plants, animals, the environment, materiel, or national security.
EPA Disinfectants Lists-Selected EPA-Registered Disinfectants. Lists (A-O) antimicrobial products registered with EPA for claims against common pathogens. Disinfectants used in UNT labs must be EPA registered and appropriate for the work being done.
Gain-of-Function (GOF) Research-Gain-of-function (GOF) studies, or research that improves the ability of a pathogen to cause disease, help define the fundamental nature of human-pathogen interactions, thereby enabling assessment of the pandemic potential of emerging infectious agents, informing public health and preparedness efforts, and furthering medical countermeasure development.
Laboratory Biorisk Management Standard-Management standard based on a management system approach.
NIH Biological Materials Shipping-Website providing information on rules and regulations related to shipping of biologicals.
NIH Laboratory Design Requirements Manual - This manual provides guidance and standards which represent the best practices in facility design, the design team assembled over 200 professionals from industry, academia, and government including designers, architects, engineers, researchers, veterinarians, maintenance staff, biosafety specialists, and others; all with expertise in a variety of disciplines and unique insights into the complicated design, construction, and functional issues involved in building NIH facilities to write this manual.
NIH/Office of Science Policy NIH Guidelines for research involving rDNA and Synthetic Nucleic Acids-Link to NIH resources related to the NIH Guidelines.
Pathogen Safety Data Sheets-Website that allows users to look up agents and provides the hazardous properties and provides recommendations for work involving the agent in a lab setting (risk assessment)
UNT EHS Waste Management- Hazardous waste resources. Links to hazardous waste pickup requests, satellite accumulation area signage, and waste labels may be found here.
Viral Vector Training - This online training has five modules. The first one is an introduction to viral vector technology and how to assess its risks. The following modules provide information on the commonly used viral vectors systems (lentivirus, gamma-retrovirus, adenovirus and AAV). At the end of each training module, there are practice exercises. Also, printable copies of the modules are provided.
Animal Research
Animal Biosafety Videos-Safety videos for those who work in animal laboratories.
UNT IACUC-Link to UNT's IACUC web pages. IACUC procedures, forms, templates, and much other useful information can be found here.
Viral Vector Training - This online training has five modules. The first one is an introduction to viral vector technology and how to assess its risks. The following modules provide information on the commonly used viral vectors systems (lentivirus, gamma-retrovirus, adenovirus and AAV). At the end of each training module, there are practice exercises. Also, printable copies of the modules are provided.
Dual-Use and Select Agents
Dual Use Research of Concern (DURC)-Dual use research of concern (DURC) is life sciences research that, based on current understanding, can be reasonably anticipated to provide knowledge, information, products, or technologies that could be directly misapplied to pose a significant threat with broad potential consequences to public health and safety, agricultural crops and other plants, animals, the environment, materiel, or national security.
Dual-Use Research-NIH Information on oversight related to Dual Use Resarch
DURC Policy-US Government Policy for Institutional Oversight of LIfe Sciences Dual Use Research of Concern
Federal Select Agent Program-Link to the Federal Select Agent Program website
Gain-of-Function (GOF) Research-Gain-of-function (GOF) studies, or research that improves the ability of a pathogen to cause disease, help define the fundamental nature of human-pathogen interactions, thereby enabling assessment of the pandemic potential of emerging infectious agents, informing public health and preparedness efforts, and furthering medical countermeasure development.
Training (Outside sources)
Biosafety Cabinet Training Video-link to video for ASU's biosafety cabinet (BSC) training, recommended for anyone who uses or plans to use a BSC.
Fundamentals of Personal Protective Equipment (PPE) in Clinical Laboratories - Safety is imperative when working with potentially harmful materials and other hazards in the laboratory. This course is designed to assist clinical and public health laboratory professionals with applying risk management strategies to identify hazards, assess risks, and select appropriate personal protective equipment options.
Basic Molecular Biology Module 1: Basic Science - Learn information on the fundamental characteristics of DNA and RNA, nucleotide base-pairing rules, and the basic techniques and workflow applied in molecular diagnostics.
Basic Molecular Biology Module 2: Laboratory Practice - Learn information on general laboratory practices. Topics covered include biosafety practices, laboratory area flow, and practices to minimize contamination.
Basic Molecular Biology Module 3: Nucleic Acid Extraction - Learn information on nucleic acid extraction. Topics covered include extraction method selection, basic extraction steps, and nucleic acid analysis.
Basic Molecular Biology Module 4: PCR and Real-Time PCR - Learn information on the principle of PCR and real-time PCR. Topics covered include PCR steps, PCR product analysis, real-time PCR characteristics.
Fundamentals of Working Safely in a Biological Safety Cabinet - Learn how to work safely in a Class II biological safety cabinet (BSC).
Fundamentals of Chemical Fume Hood Safety - Learn the major components of a chemical fume hood and proper practices for its safe and effective operation.
Fundamentals of Centrifuge Safety - Learn the major parts of a centrifuge, types of centrifuges, potential hazards, how to work safely with a centrifuge, and what to do if there is an emergency.
Good Laboratory Practice Recommendations for Biochemical Genetic Testing: Preanalytic Phase - Learn an overview of the quality practices in the preanalytic phase of biochemical genetic testing.
Good Laboratory Practices for Molecular Genetics Testing - Learn to develop procedures and processes for a molecular genetic test which are consistent with regulatory requirements and good laboratory practices.
Viral Vector Training - This online training has five modules. The first one is an introduction to viral vector technology and how to assess its risks. The following modules provide information on the commonly used viral vectors systems (lentivirus, gamma-retrovirus, adenovirus and AAV). At the end of each training module, there are practice exercises. Also, printable copies of the modules are provided.